RESUMO
Calcium pantothenate (CAS no. 137-08-6) is the calcium salt of pantothenic acid (vitamin B5). It is used in cosmetics due to its anti-static and hair conditioning properties. A 53-year-old female nurse's aide presented with intermittent facial eruptions (Figure S1). Patch tests were positive to calcium pantothenate, an ingredient of two of her products (a cleansing milk and a facial tonic). To our knowledge, no previous cases of sensitization from calcium pantothenate have been reported except for one case of systemic dermatitis from a nutritional supplement in a dexpanthenol-sensitized patient.
Assuntos
Cosméticos/efeitos adversos , Dermatite Alérgica de Contato/etiologia , Dermatoses Faciais/induzido quimicamente , Ácido Pantotênico/efeitos adversos , Complexo Vitamínico B/efeitos adversos , Diagnóstico Tardio , Dermatite Alérgica de Contato/diagnóstico , Dermatoses Faciais/diagnóstico , Feminino , Humanos , Pessoa de Meia-Idade , Testes do EmplastroAssuntos
Abdome Agudo/etiologia , Adenocarcinoma de Pulmão/secundário , Neoplasias do Jejuno/secundário , Neoplasias Pulmonares/patologia , Doenças Raras/complicações , Adenocarcinoma de Pulmão/diagnóstico por imagem , Neoplasias Encefálicas/secundário , Evolução Fatal , Feminino , Humanos , Neoplasias do Jejuno/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios XRESUMO
BACKGROUND: Liver metastases emerge during the course of colorectal cancer (CRC) in 25-50% of patients. A small proportion of patients present intrabiliary growth. The absence of large series means that little is known about intrabiliary metastasis (IBM), its radiological diagnosis, the most suitable surgical techniques, and its prognostic implications. METHODS: A systematic search without limits was performed. The studies selected included patients with a diagnosis of CRC and associated IBM, either synchronous or metachronous. RESULTS: Of 40 studies selected, 30 were case reports and 10 case series. The median time between diagnosis and IBM was 46.7 months (range 0-180). Most CRC metastases are CK7-/CK20+. Surgical treatment performed ranged from endoscopic resection to major hepatic resections combined with pancreatectomies. It seems that patients with IBM have a better survival than patients without this metastasis. CONCLUSION: In a patient with a history of CRC presenting dilatation of the bile duct, IBM should be considered. More studies are needed to determine the most appropriate type of liver resection. It is also necessary to standardize the definition and terminology of this pathology, since the existing definitions may cause confusion and make it difficult to carry out case studies and case series.
Assuntos
Neoplasias do Sistema Biliar/secundário , Neoplasias Colorretais/patologia , Neoplasias do Sistema Biliar/diagnóstico por imagem , Neoplasias do Sistema Biliar/cirurgia , Biomarcadores Tumorais/metabolismo , Hepatectomia/métodos , Humanos , Queratinas/metabolismo , PrognósticoRESUMO
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Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Amiloidose/diagnóstico por imagem , Pâncreas/diagnóstico por imagem , Pâncreas/patologia , Imageamento por Ressonância Magnética , Diagnóstico DiferencialRESUMO
Toxoplasma gondii es un protozoo intracelular con elevada prevalencia mundial. La primoinfección en inmunocompetentes puede producir linfadenopatía cervical con microgranulomas, sin necrosis ni células gigantes. En inmunodeprimidos y recién nacidos de madres infectadas durante el embarazo puede producir meningoencefalitis necrosante y afectación multivisceral, donde el microorganismo es visualizado fácilmente. Material y método. Se revisaron los hallazgos anatomopatológicos de los casos de toxoplasmosis del Hospital La Paz (1967-2010). Resultados. Se encontraron 78 casos diagnosticados de toxoplasmosis: 32 necropsias (16 toxoplasmosis congénita y 16 adultos con sida) y 46 biopsias (entre ellas 35 linfadenopatías). Conclusiones. Se describen los hallazgos anatomopatológicos de una serie amplia de toxoplasmosis. La linfadenopatía tipo Piringer-Kuchinka y la encefalitis fueron los cuadros más frecuentes(AU)
